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 Welcome to the University of Wisconsin Department of Pharmacology website. The exciting discipline of Pharmacology is well represented in our Department in the broad research and teaching areas of Neuropharmacology, Cardiovascular Pharmacology, Cancer Pharmacology, Drug Metabolism and Chemotherapy. A newly defined research area of Systems Pharmacology embraces each of these Pharmacology disciplines with a focus on understanding inter and intra cellular signaling pathways that are regulated by endogenous molecules and therapeutic agents. In addition to excellence in instruction and training in the primary discipline areas of Pharmacology, the mission of the Department of Pharmacology is to create new knowledge through preeminence in research. We feature outstanding faculty in the Department of Pharmacology who interact collaboratively with colleagues campus wide some of whom are jointly appointed in the Department of Pharmacology. These faculty from related disciplines such as Physiology, Pathology Chemistry, Biomedical Engineering and Ophthamology compliment the overall theme of cellular signal transduction. The National Institutes of Health funded interdisciplinary graduate PhD training program in Molecular and Cellular Pharmacology offers significant opportunities for graduate studies in Pharmacology at the University of Wisconsin. Our ultimate goal as molecular pharmacologists is to find links in signal transduction cascades where molecular connections become non functional due to disease or genetic mutations. These defective links are often the best targets for therapeutic interventions. Once the targets are identified, the drug discovery process can be initiated in partnerships between academia and industry to develop new medications to correct the defect.
Sincerely,
Arnold E. Ruoho,
S. Jonathan Singer Professor and
Chair of Pharmacology
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Updated every January, April, July, and October Beginning 2010.
Ruoho's lab finds important discovery
- Ruoho's lab has discovered a new class of compounds that have a high affinity inhibitors of the sigma 1 receptor. The new class of compounds inhibits the activity of the sigma receptor and WARF has applied for a patent on behalf of the inventors. (A. Ruoho, A. Hajipour, U. Chu and D. Fontanilla) We will post updates as they become available.
- The Bill and Melinda Gates foundation, which began in 1999, presented a Gates Millennium Scholarship to Uyen Chu, Ph.D. student in Pharmacology. Ms. Chu, a member of Arnold Ruoho's lab, volunteers in the oncology unit of the American Family Children's Hospital. This scholarship is given to minority students to assist them financially.
- The NIH Kirschstein NRSA Award was given to Dominique Fontanilla for 2007-10. Recently, Ms. Fontanilla also received the Jerzy E. Rose Award for excellence in neuroscience research. Dominque is also a member of Arnold Ruoho's lab.
- Richard A. Anderson presented at the European Molecular Biology Organization's Workshop at the Brasenose College in Oxford, UK. His presentation title was 'A Phosphoinositide Regulated Poly(A) Polymerase Controls 3' - Processing of Select Messages. Colleagues, Robert Landlick and Marvin Wickins of the Biochemistry Department at UW-Madison, also gave presentations at the EMBO Workshop.
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